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Lipids Health Dis ; 14: 62, 2015 Jun 24.
Artigo em Inglês | MEDLINE | ID: mdl-26104466

RESUMO

BACKGROUND: The polycystic ovary syndrome (PCOS) is considered the most common endocrine disease during the woman's reproductive life, with prevalence ranging from 5 to 10% of women of reproductive age. There is a paucity of studies regarding the use of the lipid accumulation product (LAP) as a risk marker for the development of cardiovascular disease (CVD). METHODS: A cross-sectional study was conducted on 78 women aged 18 to 42 years seen at University Hospital of Maranhão, with a diagnosis of polycystic ovary syndrome according to the Rotterdam criteria. The following variables of interest were recorded on a protocol form: sociodemographic and behavioral data, body mass index, waist circumference, fasting glucose, total cholesterol, triglycerides, low density lipoprotein cholesterol, high-density lipoprotein cholesterol, and systolic and diastolic blood pressure. RESULTS: Logistic regression showed that, except for HDL, all cardiovascular risk markers presented a higher chance of being altered when the lipid accumulation product was above the cut off value of 37.9 cm.mmol/L. CONCLUSION: The lipid accumulation product seems to be sufficient to indicate a risk of cardiovascular diseases in women with polycystic ovary syndrome.


Assuntos
Biomarcadores/metabolismo , Doenças Cardiovasculares/complicações , Doenças Cardiovasculares/metabolismo , Produto da Acumulação Lipídica , Síndrome do Ovário Policístico/complicações , Síndrome do Ovário Policístico/metabolismo , Adolescente , Adulto , Demografia , Feminino , Humanos , Modelos Logísticos , Curva ROC , Fatores de Risco , Adulto Jovem
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